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Tripar
Trihexyphenidyl Hydrochloride
Description:
Trihexyphenidyl is an antispasmodic drug used as an adjunct drug in the management of parkinsonism and as a treatment for extrapyramidal symptoms caused by drugs affecting the central nervous system (CNS).
Trihexyphenidyl is an antispasmodic drug used as an adjunct drug in the management of parkinsonism and as a treatment for extrapyramidal symptoms caused by drugs affecting the central nervous system (CNS).
Indications:
Trihexyphenidyl Hydrochloride is indicated as an adjunct in the treatment of all forms of Parkinsonism (Post encephalitic, Arteriosclerotic and Idiopathic). It is often useful as adjuvant therapy when treating these forms of Parkinsonism with Levodopa. Additionally, it is indicated for the control of extrapyramidal disorders caused by some drugs such as Dibenzoxazepines, Phenothiazine, Thioxanthenes and Butyrophenones.
Trihexyphenidyl Hydrochloride is indicated as an adjunct in the treatment of all forms of Parkinsonism (Post encephalitic, Arteriosclerotic and Idiopathic). It is often useful as adjuvant therapy when treating these forms of Parkinsonism with Levodopa. Additionally, it is indicated for the control of extrapyramidal disorders caused by some drugs such as Dibenzoxazepines, Phenothiazine, Thioxanthenes and Butyrophenones.
Mode of Action:
Trihexyphenidyl is a selective M1 muscarinic acetylcholine receptor antagonist. Trihexyphenidyl Hydrochloride exerts a direct inhibitory effect upon the parasympathetic nervous system. It also has a relaxing effect on smooth musculature. Moreover, Trihexyphenidyl blocks cholinergic activity in the CNS, which is responsible for the symptoms of Parkinson's disease.
Trihexyphenidyl is a selective M1 muscarinic acetylcholine receptor antagonist. Trihexyphenidyl Hydrochloride exerts a direct inhibitory effect upon the parasympathetic nervous system. It also has a relaxing effect on smooth musculature. Moreover, Trihexyphenidyl blocks cholinergic activity in the CNS, which is responsible for the symptoms of Parkinson's disease.
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