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Relanab
Nabumetone
Description:
Relanab (Nabumetone) is an NSAID used to treat osteoarthritic and rheumatoid arthritic pain.
Relanab (Nabumetone) is an NSAID used to treat osteoarthritic and rheumatoid arthritic pain.
Indications:
Relanab (Nabumetone) is indicated for the relief of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Relanab (Nabumetone) is indicated for the relief of signs and symptoms of osteoarthritis and rheumatoid arthritis.
Mode of Action:
Relanab (Nabumetone) is a non-selective prostaglandin G/H synthase inhibitor that acts on both prostaglandin G/H synthase 1 and 2 (COX-1 and -2). Prostaglandin G/H synthase catalyzes the conversion of arachidonic acid to prostaglandin G2 and prostaglandin G2 to prostaglandin H2. Prostaglandin H2 is the precursor to a number of prostaglandins involved in fever, pain, swelling, inflammation, and platelet aggregation. The analgesic, antipyretic and anti-inflammatory effects of NSAIDs occur as a result of decreased prostaglandin synthesis.
Relanab (Nabumetone) is a non-selective prostaglandin G/H synthase inhibitor that acts on both prostaglandin G/H synthase 1 and 2 (COX-1 and -2). Prostaglandin G/H synthase catalyzes the conversion of arachidonic acid to prostaglandin G2 and prostaglandin G2 to prostaglandin H2. Prostaglandin H2 is the precursor to a number of prostaglandins involved in fever, pain, swelling, inflammation, and platelet aggregation. The analgesic, antipyretic and anti-inflammatory effects of NSAIDs occur as a result of decreased prostaglandin synthesis.
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