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Olzap
Olanzapine
Description:
Olanzapine is a selective monoaminergic antagonist with high affinity binding to serotonin 5-HT, dopamine, muscarinic, H1 and alpha receptors. It has weak binding affinity to GABA-A, benzodiazepine and beta adrenergic receptors.
Olanzapine is a selective monoaminergic antagonist with high affinity binding to serotonin 5-HT, dopamine, muscarinic, H1 and alpha receptors. It has weak binding affinity to GABA-A, benzodiazepine and beta adrenergic receptors.
Indications:
- Schizophrenia
- Bipolar disorder
- Mania
Mode of Action:
The mechanism of action of olanzapine, as with other drugs having efficacy in schizophrenia, is unknown. However, it has been proposed that this drug's efficacy in schizophrenia is mediated through a combination of dopamine and serotonin type 2 (5HT2) receptor site antagonism.
The mechanism of action of olanzapine, as with other drugs having efficacy in schizophrenia, is unknown. However, it has been proposed that this drug's efficacy in schizophrenia is mediated through a combination of dopamine and serotonin type 2 (5HT2) receptor site antagonism.
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