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Nebilol Plus
Nebivolol Hydrochloride + Hydrochlorothiazide
Description:
Nebilol Plus is a fixed dose combination of Nebivolol & Hydrochlorothiazide. Nebivolol is a racemate of two enantiomers, d-nebivolol and l-nebivolol. Nebivolol has unique pharmacologic properties, including very high selectivity for beta-1 receptor and nitric oxide-mediated vasodilatory effect. Nebivolol reduces heart rate & blood pressure at rest & during exercise significantly & Hydrochlorothiazide is a thiazide type diuretic also used in hypertension.
Nebilol Plus is a fixed dose combination of Nebivolol & Hydrochlorothiazide. Nebivolol is a racemate of two enantiomers, d-nebivolol and l-nebivolol. Nebivolol has unique pharmacologic properties, including very high selectivity for beta-1 receptor and nitric oxide-mediated vasodilatory effect. Nebivolol reduces heart rate & blood pressure at rest & during exercise significantly & Hydrochlorothiazide is a thiazide type diuretic also used in hypertension.
Indications:
Nebilol Plus is indicated in treatment of essential hypertension & treatment of stable mild and moderate chronic heart failure.
Nebilol Plus is indicated in treatment of essential hypertension & treatment of stable mild and moderate chronic heart failure.
Mode of Action:
The mechanism of action of the antihypertensive response of Nebivolol tablets has not been definitively established. Possible factors that may be involved include- (1) decreased heart rate (2) decreased myocardial contractility (3) diminution of tonic sympathetic outflow to the periphery from cerebral vasomotor centers (4) suppression of renin activity and (5) vasodilation and decreased peripheral vascular resistance. Hydrochlorothiazide is a novel diuretic which affects the distal renal tubular mechanism of electrolyte reabsorption and resulting reduce blood volume or Cardiac Output.
The mechanism of action of the antihypertensive response of Nebivolol tablets has not been definitively established. Possible factors that may be involved include- (1) decreased heart rate (2) decreased myocardial contractility (3) diminution of tonic sympathetic outflow to the periphery from cerebral vasomotor centers (4) suppression of renin activity and (5) vasodilation and decreased peripheral vascular resistance. Hydrochlorothiazide is a novel diuretic which affects the distal renal tubular mechanism of electrolyte reabsorption and resulting reduce blood volume or Cardiac Output.
Different Dosages from Nebilol Plus
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