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Glizid MR
Gliclazide
Description:
Gliclazide (Glizid MR) is white, oblong, biconvex tablet. Gliclazide is a second-generation sulfonylurea derivative used in type2 diabetes and acts primarily by increasing insulin secretion from functioning pancreatic beta cell.
Gliclazide (Glizid MR) is white, oblong, biconvex tablet. Gliclazide is a second-generation sulfonylurea derivative used in type2 diabetes and acts primarily by increasing insulin secretion from functioning pancreatic beta cell.
Indications:
This medication is indicated for type 2 diabetes mellitus, in association with dietary measures and with physical exercise when these measures alone are not sufficient to obtain normal blood glucose level.
This medication is indicated for type 2 diabetes mellitus, in association with dietary measures and with physical exercise when these measures alone are not sufficient to obtain normal blood glucose level.
Mode of Action:
Gliclazide (Glizid MR) appears to have several mode of action, apparently mediated by inhibition of ATP-sensitive potassium channels. Initially, secretion of insulin by functioning islet beta cells is increased. However, insulin secretion subsequently falls again but the hypoglycemic effect persists and may be due to inhibition of hepatic glucose production.
Gliclazide (Glizid MR) appears to have several mode of action, apparently mediated by inhibition of ATP-sensitive potassium channels. Initially, secretion of insulin by functioning islet beta cells is increased. However, insulin secretion subsequently falls again but the hypoglycemic effect persists and may be due to inhibition of hepatic glucose production.
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