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Liconor
Ursodeoxycholic Acid
Description:
Ursodeoxycholic acid (Liconor) is a naturally occuring bile acid used to treat different hepatobilliary disorders.
Ursodeoxycholic acid (Liconor) is a naturally occuring bile acid used to treat different hepatobilliary disorders.
Indications:
Licono 150 & 300 mg tablet is a superior drug for the treatment of Cholestasis (Jaundice), Acute Viral Hepatitis, Viral Hepatitis, Chronic Hepatitis, Chronic Hepatitis C, Alcoholic Fatty Liver, Primary Billiary Cirrhosis (PBC), Primary Sclerosing Cholangitis (PSC), Dissolution of gallstones and Non-alcoholic steato hepatitis (NASH). Liconor Suspension is the drug of choice for the treatment of Cholestasis (Jaundice), Primary Billiary Cirrhosis, Acute Viral Hepatitis, Viral Hepatitis, Chronic Hepatitis, Primary Sclerosing Cholangitis (PSC) and Dissolution of gallstones.
Licono 150 & 300 mg tablet is a superior drug for the treatment of Cholestasis (Jaundice), Acute Viral Hepatitis, Viral Hepatitis, Chronic Hepatitis, Chronic Hepatitis C, Alcoholic Fatty Liver, Primary Billiary Cirrhosis (PBC), Primary Sclerosing Cholangitis (PSC), Dissolution of gallstones and Non-alcoholic steato hepatitis (NASH). Liconor Suspension is the drug of choice for the treatment of Cholestasis (Jaundice), Primary Billiary Cirrhosis, Acute Viral Hepatitis, Viral Hepatitis, Chronic Hepatitis, Primary Sclerosing Cholangitis (PSC) and Dissolution of gallstones.
Mode of Action:
The activity of Ursodeoxycholic acid (Liconor) is achieved through a decrease in secretion of cholesterol in bile. Ursodeoxycholic acid achieves this through a few mechanisms. It reduces cholesterol absorption, suppresses liver cholesterol synthesis and it does not inhibit bile acid synthesis. Therefore, alters bile composition from supersaturated to unsaturated. Ursodeoxycholic acid also promotes the formation of liquid cholesterol crystal complexes which enhance removal of the cholesterol from the gallbladder into the intestine to be expelled. Ursodeoxycholic acid improves cholestatic liver diseases by-
The activity of Ursodeoxycholic acid (Liconor) is achieved through a decrease in secretion of cholesterol in bile. Ursodeoxycholic acid achieves this through a few mechanisms. It reduces cholesterol absorption, suppresses liver cholesterol synthesis and it does not inhibit bile acid synthesis. Therefore, alters bile composition from supersaturated to unsaturated. Ursodeoxycholic acid also promotes the formation of liquid cholesterol crystal complexes which enhance removal of the cholesterol from the gallbladder into the intestine to be expelled. Ursodeoxycholic acid improves cholestatic liver diseases by-
- Protecting cholangiocytes against cytotoxicity of hydrophobic bile acids
- Stimulating hepatobilliary secretion
- Protecting hepatocytes against bile acid-induced apoptosis.
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