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Empadus
Empagliflozin
Description:
Empagliflozin is an orally-active inhibitor of the sodium-glucose co-transporter 2 {SGLT2) expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen.
Empagliflozin is an orally-active inhibitor of the sodium-glucose co-transporter 2 {SGLT2) expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen.
Indications:
- An addition to diet and exercise to improve glycemic control in adults with type-2 diabetes mellitus.
- Also indicated to reduce the risk of cardiovascular death in adult patients with type-2 diabetes mellitus and cardiovascular disease.
Mode of Action:
Empagliflozin is an inhibitor of SGLT2. By inhibiting SGLT2, Empagliflozin reduces renal reabsorption of filtered glucose and lowers the renal threshold for glucose and thereby increases urinary glucose excretion.
Empagliflozin is an inhibitor of SGLT2. By inhibiting SGLT2, Empagliflozin reduces renal reabsorption of filtered glucose and lowers the renal threshold for glucose and thereby increases urinary glucose excretion.
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