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Topimax
Topiramate USP
Description:
Topiramate is a sulfamate substituted monosaccharide, having molecular formula C12H 21NO8S and a molecular weight of 339.363 g/mol. It is a medication used to treat epilepsy and prevent migraine & has also been used in alcohol dependency.
Topiramate is a sulfamate substituted monosaccharide, having molecular formula C12H 21NO8S and a molecular weight of 339.363 g/mol. It is a medication used to treat epilepsy and prevent migraine & has also been used in alcohol dependency.
Indications:
Topiramate is used to treat epilepsy and as an anticonvulsant in children and adults. In children, it is also indicated for the treatment of Lennox-Gastaut syndrome. It is most frequently prescribed for the prevention of migraine as it decreases the frequency of attack. One common off-label use of Topiramate is in the treatment of bipolar disorder. Other uses includes treatment of obesity and antipsychotic-induced weight gain.
Topiramate is used to treat epilepsy and as an anticonvulsant in children and adults. In children, it is also indicated for the treatment of Lennox-Gastaut syndrome. It is most frequently prescribed for the prevention of migraine as it decreases the frequency of attack. One common off-label use of Topiramate is in the treatment of bipolar disorder. Other uses includes treatment of obesity and antipsychotic-induced weight gain.
Mode of Action:
Exact pathway by which Topiramate exerts its anticonvulsant and migraine prophylaxis effects are still unknown. But, electrophysiological and biochemical evidence suggests that Topiramate blocks voltage-dependent sodium channels, increases the activity of the neurotransmitter Gamma Amino Butyrate at some subtypes of the GABA-A receptor, antagonizes the AMPA/kainate subtype of the glutamate receptor and inhibits the carbonic anhydrase enzyme.
Exact pathway by which Topiramate exerts its anticonvulsant and migraine prophylaxis effects are still unknown. But, electrophysiological and biochemical evidence suggests that Topiramate blocks voltage-dependent sodium channels, increases the activity of the neurotransmitter Gamma Amino Butyrate at some subtypes of the GABA-A receptor, antagonizes the AMPA/kainate subtype of the glutamate receptor and inhibits the carbonic anhydrase enzyme.
Different Dosages from Topimax
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- Topimax 25 mg Tablet
- Price : Tk 250.00/Box
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- Topimax 50 mg Tablet
- Price : Tk 500.00/Box
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