Description:
Guaifenesin is an expectorant. It helps loosen congestion in the chest and throat, making it easier to cough out through the mouth. Dextromethorphan Hydrobromide is a cough suppressant, it affects the signals in the brain that trigger cough reflex. Menthol is an organic compound made synthetically or obtained from cornmint, peppermint or other mint oils, it has local anesthetic and counterirritant qualities and it is widely used to relieve minor throat irritation.

Indications:
Chest congestion Cough Sore throat.

Mode of Action:
Dextromethorphan Hydrobromide is a drug of the morphinan class with sedative, dissociative, and stimulant properties (at higher doses). It is a cough suppressant in many over-the-counter cold. Dextromethorphan Hydrobromide works by decreasing activity in the part of the brain that causes coughing. Guaifenesin is thought to act as an expectorant by increasing the volume and reducing the viscosity of secretions in the trachea and bronchi. It has been said to aid in the flow of respiratory tract secretions, allowing ciliary movement to carry the loosened secretions upward toward the pharynx. Menthol primarily activates the cold-sensitive TRPM8 receptors in the skin. Menthol, after topical application, causes a feeling of coolness due to stimulation of 'cold' receptors by inhibiting Ca++ currents of neuronal membranes.

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