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Amocal-AT
Amlodipine + Atenolol
Description:
It is a fixed-dose combination containing Amlodipine and Atenolol. Amlodipine is a dihydropyridine calcium antagonist, Atenolol is a cardio-selective beta-blocker,
It is a fixed-dose combination containing Amlodipine and Atenolol. Amlodipine is a dihydropyridine calcium antagonist, Atenolol is a cardio-selective beta-blocker,
Indications:
Essential hypertension, Angina pectoris & hypertension as co-existing diseases, Post Myocardial Infarction.
Essential hypertension, Angina pectoris & hypertension as co-existing diseases, Post Myocardial Infarction.
Mode of Action:
Amlodipine inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. It has a greater effect on vascular smooth muscle than on cardiac muscle. Atenolol causes a reduction in blood pressure by lowering cardiac output, decreasing the plasma renin activity and sympathetic outflow from CNS
Amlodipine inhibits the transmembrane influx of calcium ions into vascular smooth muscle and cardiac muscle. It has a greater effect on vascular smooth muscle than on cardiac muscle. Atenolol causes a reduction in blood pressure by lowering cardiac output, decreasing the plasma renin activity and sympathetic outflow from CNS
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